Sale and Worcester have been drawn in the same pool for next season's Amlin Challenge Cup.
A losing bonus point for Montpellier in Bayonne was enough to eliminate Perpignan from the race for the play-offs.
Second takes on third in the pick of the Top 14 fixtures with Clermont set to entertain Toulouse on Saturday.
A last-gasp try from Vincent Clerc saw Toulouse claim a 27-26 win over Racing Metro, ending the Parisians' winning run.
London Irish have signed hooker Michael Mayhew from Newcastle and he will leave the Falcons at the end of the season.
Toulon ran in six tries in a comprehensive 50-15 thumping of Biarritz at the Stade Mayol in the Top 14 on Saturday.
Top 14 leaders Toulon host Biarritz this weekend before fourth-placed Castres face the unenviable task of travelling to Clermont.
Clermont notched up a bonus-point win over Stade Francais while Toulon beat Toulouse in Saturday's Top 14 action.
Leaders Toulon will take on fourth-placed Castres on Friday in the pick of the weekend's Top 14 action.
Stade Francais remain in the Top 14 play-off picture after a backs-to-the-wall victory over Bordeaux.
The Top 14 action gets underway on Friday when Toulouse look to maintain their impressive home record over Perpignan.
There were plenty of upsets in the Top 14 on Saturday with leaders Toulon thrashed 41-0 by Bordeaux-Begles.
There are plenty of intriguing ties in the Top 14 this weekend, starting with Clermont travelling to Racing on Friday.
Perpignan stayed in the race for the Top 14 play-offs thanks to a hard-fought 26-19 win over high-flying Clermont on Friday.
London Irish ended their Amlin Challenge Cup campaign on a high with a 17-7 win over French side Bordeaux-Begles.
London Irish have recalled winger Topsy Ojo for their final Amlin Challenge Cup group match against Bordeaux.
Freddie Burns kicked two late penalties as Gloucester beat Bordeaux to make the Amlin Challenge Cup quarter-finals.
Gloucester will look to secure their place in the quarter-finals of the Amlin Challenge Cup when they tackle Bordeaux.
Grenoble claimed yet another big scalp as they maintained their unbeaten home record with victory over Castres.
Top 14 action continues as Toulon look to keep their lead at the summit ahead of the final break before the Heineken Cup Pool run-in.